Upstate South Carolina Vacation Packages 2026 from $476

Upstate South Carolina flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Charlotte Marriott City Center

Uptown Charlotte

Save 100% on your flight

$476

per person

Oct 23 - Oct 26

found 1 day ago

Roundtrip flight included

Baltimore (BWI) to Charlotte (CLT)

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. A coffee shop, a snack bar/deli, and a grocery/convenience store are also on offer.

The Westin Charlotte

Uptown Charlotte

Save 100% on your flight

$548

per person

Oct 23 - Oct 26

found 1 day ago

Roundtrip flight included

Baltimore (BWI) to Charlotte (CLT)

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Self parking, a snack bar/deli, and express check-out are also offered.

The Restoration Asheville

Downtown Asheville

Save 100% on your flight

$814

per person

Dec 1 - Dec 5

found 18 hours ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Asheville (AVL)

This smoke-free hotel's 3 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. There's fun for all ages with a bowling alley and an arcade/game room. Enjoy the a rooftop terrace and free perks like continental breakfast and an area shuttle.

Grand Bohemian Lodge Asheville, Autograph Collection®

Biltmore Village

Save 100% on your flight

$1,259

per person

Dec 1 - Dec 5

found 10 hours ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Asheville (AVL)

A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. There's a bar/lounge on site, and a 24-hour front desk and laundry facilities are also provided.

The Windsor Boutique Hotel

Downtown Asheville

$1,036

per person

Dec 1 - Dec 5

found 10 hours ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Asheville (AVL)

This hotel features a bar/lounge, free WiFi in public areas, and a snack bar/deli. If you want to take your pet along, this pet-friendly property offers everything you'll need for your pet including food and water bowls. Luggage storage, laundry facilities, and concierge services are also on offer.

Top Upstate South Carolina hotels deals

Embassy Suites Greenville Golf Resort & Conference Center

670 Verdae Blvd Greenville SC

Free Cancellation

Reserve now, pay when you stay

$108 nightly

$120 total

Oct 4 - Oct 5

Total with taxes and fees

A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Enjoy the outdoor pool and free buffet breakfast each morning.

Pool

Breakfast included

Hilton Greenville

45 W Orchard Park Dr Greenville SC

Free Cancellation

Reserve now, pay when you stay

$117 nightly

$129 total

Oct 11 - Oct 12

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, and laundry service. Self parking, a terrace, and a garden are also offered.

Pet friendly

Free WiFi

Hyatt Place Greenville/Haywood

40 W Orchard Park Dr Greenville SC

Free Cancellation

Reserve now, pay when you stay

$82 nightly

$91 total

Oct 18 - Oct 19

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the seasonal outdoor pool and free perks like buffet breakfast and free self parking.

Pool

Breakfast included

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

851 Congaree Rd Greenville SC

$99 nightly

$110 total

Oct 19 - Oct 20

Total with taxes and fees

This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Unwind with a drink at one of the 2 bars/lounges and enjoy free perks like free self parking and an area shuttle.

Pool

Free airport shuttle

Grand Bohemian Lodge Greenville, Autograph Collection

44 EAST CAMPERDOWN WAY Greenville SC

Free Cancellation

Reserve now, pay when you stay

$401 nightly

$441 total

Sep 27 - Sep 28

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. A lobby fireplace, a communal living room, and dry cleaning are also on offer.

Spa

Pet friendly

Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd Greenville SC

Free Cancellation

Reserve now, pay when you stay

$76 nightly

$84 total

Oct 4 - Oct 5

Total with taxes and fees

This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.

Pool

Breakfast included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.

See properties

Frequently asked questions

How much are vacation packages to Upstate South Carolina?

$476 is all you need to spend for an exhilarating break in Upstate South Carolina. Bundle your hotel and flights into a vacation package with Travelocity and watch how the savings start to pile up. With prices this good, you'll want to start packing your suitcase now!

Where can I get the best vacation package deals for Upstate South Carolina?

For an amazing Upstate South Carolina package deal, you can't go past Travelocity. Take your pick of 400 air carriers and 1,000,000 properties worldwide to create your dream escape — the choice is all yours!

Why should I purchase my Upstate South Carolina vacation bundle with Travelocity?

With our Price Match Guarantee, we'll match any better price you can find. Add to that our 24/7 support and top-quality service and the vacation you've been dreaming of is well within reach.

Can I save money on my Upstate South Carolina car rental if I bundle it with a hotel or flight?

You sure can. And our Upstate South Carolina vacation packages are the ideal way to do it. In only a few clicks you can save cash as well as time by bundling your bookings. Pick up the keys to your rental car then chart your own course. Searching for things to do? Throw some tours or experiences into your package and save on those too.

Which airport is best for Upstate South Carolina?

Upstate South Carolina has two major airports — Greenville-Spartanburg Intl. Airport (GSP) and Asheville Regional Airport (AVL).

What is there to do in Upstate South Carolina?

You'll be happy to know Upstate South Carolina is full to the brim with incredible photo opportunities, however Clemson University and Lake Keowee are right up there with the very best.